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Image Search Results
Journal: medRxiv
Article Title: Polymorphism in IFNAR contributes to glucocorticoid response and outcome in ARDS and COVID-19
doi: 10.1101/2022.03.10.22272123
Figure Lengend Snippet: (A ) STAT1 expression in the lung after 4-day culture in the presence of IFN beta with or without hydrocortisone (HC). ( B) pSTAT1 expression in the same specimens as in A. ( C) Example photomicrographs showing higher STAT2 expression in a TT patient than in a CT patient and the effect of HC on its nuclear translocation. Most STAT2 remains in the cytoplasm of the CT patients, whereas nuclear expression is prominent in the TT patient. Indicated insets are shown in the bottom row. Arrows. ( D ) Combined results of all patients noting that two CT samples are excluded in the data as the patients were already under glucocorticoid treatment at the time of sample acquisition. Ns, not significant; *P<0.05; **P<0.01; and ***P<0.001
Article Snippet: The first stage antibodies were anti-alpha chain of the IFN alpha/beta receptor (
Techniques: Expressing, Translocation Assay